Background: There are many factors and areas in the formation of addiction that one of the most important is the family system. Drug addiction often caught out people who are prepared to risk. The present study aims at examining relationships between differentiation of self and it's Component with addiction potential in Bojnord university students.

Materials and Methods: Statistical population in present study was all Bojnord university students in the second semester of the academic year is the 93-1392. The sample consisted of 120 students were selected by random sampling method. The Differentiation of Self Inventory (DSI) and Iranian Addiction Potential Scale (IAPS) were used to collect data. Also the data were analyzed by multiple regressions and Pearson correlation coefficient by used SPSS-19 software and validated by confirmatory factor analysis by used AMOS-21 software.

Results: Findings indicate that correlation coefficients between emotional reaction (-0.225), I-position (-0.193), emotional cutoff (-0.561), fusion with others (-0.136) with addiction potential were significant (p<0.0001). Stepwise multiple regression analyses yielded of the four components of differentiation of self, only two variables of emotional cutoff and I-position found permit entry into the regression equation (R2=0.361, p<0.0001).

Conclusion: According to the result، addiction potential of students can be predicted through differentiation and its components. Differentiation of self especially emotional cutoff and I-position were recommended in screening programs in the field of addiction.