نشریه علمی پژوهشی طب انتظامی Journal of Police Medicine
Volume 13, Issue 1 (2024)
J Police Med 2024, 13(1) |
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Ethics code: 202341801107
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زین Alizadeh1 M, Zeinoddini M, Chitsaz Sadeghi ا. The military utilization of cognitive biomarkers: Diagnostic and therapeutic methods, A non-systematic review article. J Police Med 2024; 13 (1) : e12
URL: http://jpmed.ir/article-1-1282-en.html
URL: http://jpmed.ir/article-1-1282-en.html
1- Research Center of Science and Biotechnology, Malek Ashtar University of Technology
2- Research Center of Science and Biotechnology ,zeinoddini@modares.ac.ir
2- Research Center of Science and Biotechnology ,
English Extended Abstract: (46 Views)
AIMS: Cognitive biomarkers serve as indicators for diagnosing and monitoring the progression of cognitive disorders. Military personnel may experience various behavioral disorders that impact their cognitive functions. Hence, the current study aimed to pinpoint the most crucial biomarkers and explore therapeutic possibilities derived from them to enhance the management of the specific psychological disorders under consideration.
MATERIALS AND METHODS: Keywords corresponding to post-traumatic stress disorder, major depression, and chronic stress were identified in MeSH. Subsequently, articles related to biomarkers associated with these psychological disorders and their respective medicinal compounds were explored in the Scopus, PubMed, Embase, ISI databases and Google Scholar search engine. The data obtained was then compiled and analyzed.
FINDINGS: The data indicated the presence of 56 cognitive biomarkers linked to the aforementioned disorders. These biomarkers encompass a range of indicators such as those associated with the hypothalamic-pituitary-adrenal (HPA) axis, steroid hormones, metabolic hormones, immune system, proteomics factors, inflammation factors, serotonin receptors, growth factors, autonomic nervous system, endocrine system, and antioxidants. These biomarkers are the focus of various clinical studies as potential functional biological targets for pharmaceutical compound development.
CONCLUSION: Psychological disorders can have profound implications on the well-being of military personnel and their effectiveness in carrying out duties, impacting both their own health and that of others. Hence, precise screening and identification of diagnostic factors are crucial for implementing appropriate treatment measures, particularly among military personnel.
MATERIALS AND METHODS: Keywords corresponding to post-traumatic stress disorder, major depression, and chronic stress were identified in MeSH. Subsequently, articles related to biomarkers associated with these psychological disorders and their respective medicinal compounds were explored in the Scopus, PubMed, Embase, ISI databases and Google Scholar search engine. The data obtained was then compiled and analyzed.
FINDINGS: The data indicated the presence of 56 cognitive biomarkers linked to the aforementioned disorders. These biomarkers encompass a range of indicators such as those associated with the hypothalamic-pituitary-adrenal (HPA) axis, steroid hormones, metabolic hormones, immune system, proteomics factors, inflammation factors, serotonin receptors, growth factors, autonomic nervous system, endocrine system, and antioxidants. These biomarkers are the focus of various clinical studies as potential functional biological targets for pharmaceutical compound development.
CONCLUSION: Psychological disorders can have profound implications on the well-being of military personnel and their effectiveness in carrying out duties, impacting both their own health and that of others. Hence, precise screening and identification of diagnostic factors are crucial for implementing appropriate treatment measures, particularly among military personnel.
Article number: e12
Article Type: Analytic Review |
Subject:
Police Health
Received: 2024/07/1 | Accepted: 2024/07/14 | Published: 2024/07/19
Received: 2024/07/1 | Accepted: 2024/07/14 | Published: 2024/07/19
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