نشریه علمی پژوهشی طب انتظامی Journal of Police Medicine
Volume 11, Issue 1 (2022)
J Police Med 2022, 11(1) |
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Zoghi L, Ajilchi B, Gholamalieie M. Pain Perception, Resilience, Failure Tolerance and Aggression of Women and Men Treated with Methadone in Tehran, Iran. J Police Med 2022; 11 (1) : e12
URL: http://jpmed.ir/article-1-1056-en.html
URL: http://jpmed.ir/article-1-1056-en.html
1- Department of Psychology, Faculty of Human Resources, Amin University of Police, Tehran, Iran
2- Department of Motor Behavior, Faculty of Physical Education and Sport Sciences, Allameh Tabatabaei University, Tehran, Iran ,Ajilchi_b@yahoo.com
3- Department of General Psychology, Islamic Azad University, Central Branch, Tehran, Iran
2- Department of Motor Behavior, Faculty of Physical Education and Sport Sciences, Allameh Tabatabaei University, Tehran, Iran ,
3- Department of General Psychology, Islamic Azad University, Central Branch, Tehran, Iran
English Extended Abstract: (1763 Views)
Introduction
... [1, 2]. Among the very limited treatment options for substance abuse, a methadone maintenance program is an effective drug treatment that leads to the gradual replacement of opioids with methadone to reduce abuse [1, 3]. Based on research evidence, physiological and epidemiological dimensions of substance abuse and its treatment are different in men and women due to external and internal factors [4]. ... [9-5]. One of the effective factors in drug abuse is pain perception [10]. ... [11]. Studies have shown that people with intolerance or low resilience turn to drugs to reduce the pain and stress caused by physical and psychological illnesses [12]. ... [13-16]. They are also more likely to fail, and this can lead to increased drug use and addiction [17, 18]. ... [19-22]. Failure and other negative emotions such as depression and irritability are common causes for aggression [23]. ... [24-27].
Aim (s)
This study aimed to compare the psychological variables of pain perception, resilience, failure tolerance, and aggression in women and men with methadone treatment.
Research Type
This research is descriptive research with a causal-comparative method.
Research Society, Place and Time
The statistical population of the present study was men and women with drug abuse in Tehran who had referred to addiction treatment clinics in the summer and autumn of 2019.
Sampling Method and Number
To select the sample group by multi-stage random cluster sampling method, in the first stage, out of 22 districts of Tehran Municipality and in the second stage, among addiction treatment centers in control of the supervision of the Association of Addiction Treatment Centers in each of these areas, a clinic (Three clinics in total) and in the third stage, 300 people, including 150 men and 150 women, were randomly selected from the people treated with methadone in these selected centers. .... [27].
Used Devices & Materials
McGill pain scale [28, 29] with Cronbach's alpha 0.87, Connor and Davidson resilience scale [30] with Cronbach's alpha 0.84, failure tolerance questionnaire [31, 32] with Cronbach's alpha 0.72, and Bass and Perry aggression questionnaire [33, 34] with Cronbach's alpha of 0.71, were the tools used in this study.
Statistical Analysis
After examining the assumptions of parametric tests such as continuity of variables in terms of measurement and normalization of data distribution using Kolmogorov-Smirnov test and establishing homogeneity of variance of variables also the similarity of the two groups in demographic variables of age, education, and work experience, Paired sample t-test was used for data analysis.
Finding by Text
The highest frequency among the 300 samples, (42%) was related to people between 22 and 26 years (126 people), with bachelor's degree (141 people; 47%) and 11 to 15 years of work experience (150 people; 50%) and the lowest frequency was between 32 and 36 years old, with Ph.D. and above 15 years of work experience (Table 1). The normality of the data distribution of variables was checked and confirmed by the Kolmogorov-Smirnov test (p>0.05). The mean of all variables of the study was different in men and women, but only the difference between pain perception, failure tolerance, and aggression with values was respectively 4.152±0.521, 4.208±0.303 and 3.621 21±0.211 which were significant in women and 3.258±0.359, 3.247±0.137, and 4.188±652 in men who treated with methadone maintenance program at the level of p<0.05 (Table 2). Mean values showed that in women, pain perception and tolerance of failure were more and less aggression compared to men (p<0.05) but no significant difference was observed between resilience between women and men (p >0.05; Table 2).
Main Comparison to the Similar Studies
According to the results of this study, for women, the process of quitting methadone is more difficult than for men. In general, the results of the study are consistent with studies that have confirmed gender differences in substance abuse disorders and their treatment [4] … [5]. Researchers have shown that the brain is a biological process that triggers addiction and the capacity to change behavior [35]. Therefore the perspective of the nervous system and biology improves the study from a scientific perspective. In explaining the results of the present study, this view has been tried to be considered. The first finding of the present study was a higher perception of pain in women addicted to methadone than men. Studies show that pain tolerance is lower in people with methadone addiction than in normal people [36]. While pain tolerance is different in men and women; although the difference in pain sensitivity and perception between men and women is partly due to social conditions and psychosocial factors, many laboratory studies have attributed this difference to biological mechanisms and sex hormones [37]. The results of studies show that gender differences in pain and its relief are due to an interaction between genetic, anatomical, physiological, neurological, hormonal, psychological, and social factors that regulate pain differently in both sexes [38]. ... [39, 40]. The present study also showed a higher rate of pain perception in women treated with methadone compared to men. This finding can be explained by examining the status of the menstrual cycle of women in the sample group and the effects of estrogen on pain sensation and perception and its interaction with the analgesic properties of methadone in women's pain tolerance. Another result showed that the resilience of addicted men and women treated with methadone was not different. Evidence shows that resilience is affected by gender and in comparison with men, women show different reactions in stressful situations [41]. However, such a result was not obtained in this study. Perhaps this difference can be related to the cultural, educational, and socio-economic status of the sample group. This result can also be attributed to the equal desire of men and women for withdrawal. This finding can be interpreted positively, as this lack of differences in the resilience of men and women in the process of quitting substance abuse can indicate a reduction in non-biological gender differences. Differences such as differences in psychological abilities as internal factors and differences in negative outlook and other cultural and social gender factors as external factors. Another finding of the present study was that failure tolerance was lower in women with methadone treatment substance abuse disorders compared to men. According to the behavioral inhibitor and behavioral activator brain systems presented in reinforcement sensitivity theory, the behavioral inhibitor system is more active in women than men. As a result, women are more likely to fail or feel frustrated. When addicted people are in the process of withdrawal, the activity of the behavioral inhibition system increases due to the lack of drugs, in other words, the lack of rewards. Increased activity of this system in men is considered inactivity in the male brain system and reduces the severity of the behavioral activation system, but in women, it doubles the activity of the inhibitory system and causes more severe failure symptoms in women. ... [42]. When quitting methadone, due to the presence of a pleasant stimulus with reward symptoms, namely methadone, the behavioral activation system in people quitting with methadone is activated. On the other hand, due to the limited consumption in terms of the amount of substance consumed and the time of consumption, the behavioral inhibition system becomes more active. The behavioral activation system has a facilitating role in the activity of the behavioral inhibition system and raises the level of activity of the behavioral inhibition system. Due to the higher level of behavioral inhibition system in women in normal situation, the increased activity of this system is doubled and leads to much greater failure in women treated with methadone than in men. The more severe the failure, the more difficult it is to tolerate and the more intolerant the failure, and this is what happens to women on methadone treatment compared to men. The latest finding of the present study was a higher rate of aggression in methadone-addicted men compared to their female counterparts. Higher levels of anger, aggression, and aggressive and harmful behaviors in men than in women can be attributed to higher levels of the male hormone testosterone in men. In addition, men are considered to be stronger and more superior due to their mainly larger physical appearance, more voluminous muscles, and more physical strength. ... [43]. Because in the present study, men felt more failure than women, consequently, the aggression that led to the feeling of failure was more in men than women.
Limitations
The limitations of the present study include not considering variables such as marital status, type of job and income, having or not having children, duration of addiction, amount of substance used before entering the treatment plan, number of withdrawal measures, and types of previous methods for quitting, that can have many effects on the study.
Suggestions
It is suggested that in future research, anxiety and anger control training be performed in treated men. The implementation of failure protocols based on different psychological approaches in women treated with methadone is also suggested in future studies.
Conclusions
In the process of methadone withdrawal, women perceive more pain and tolerate less failure than men, and men are more aggressive than women. Therefore, the process of methadone withdrawal seems to be more difficult for women than men.
Clinical & Practical Tips in Police Medicine
The use of the results of the present study in the treatment of criminals with drug abuse can be expressed according to their gender in police medical centers and other medical units of the police force.
Acknowledgments
We would like to thank all the participants who contributed to this research.
Conflict of Interest
The authors state that there is no conflict of interest in the present study.
Funding Sources
The present study had no financial support.
Table 2) Descriptive indicators of research variables by group
with the results of independent t-test
... [1, 2]. Among the very limited treatment options for substance abuse, a methadone maintenance program is an effective drug treatment that leads to the gradual replacement of opioids with methadone to reduce abuse [1, 3]. Based on research evidence, physiological and epidemiological dimensions of substance abuse and its treatment are different in men and women due to external and internal factors [4]. ... [9-5]. One of the effective factors in drug abuse is pain perception [10]. ... [11]. Studies have shown that people with intolerance or low resilience turn to drugs to reduce the pain and stress caused by physical and psychological illnesses [12]. ... [13-16]. They are also more likely to fail, and this can lead to increased drug use and addiction [17, 18]. ... [19-22]. Failure and other negative emotions such as depression and irritability are common causes for aggression [23]. ... [24-27].
Aim (s)
This study aimed to compare the psychological variables of pain perception, resilience, failure tolerance, and aggression in women and men with methadone treatment.
Research Type
This research is descriptive research with a causal-comparative method.
Research Society, Place and Time
The statistical population of the present study was men and women with drug abuse in Tehran who had referred to addiction treatment clinics in the summer and autumn of 2019.
Sampling Method and Number
To select the sample group by multi-stage random cluster sampling method, in the first stage, out of 22 districts of Tehran Municipality and in the second stage, among addiction treatment centers in control of the supervision of the Association of Addiction Treatment Centers in each of these areas, a clinic (Three clinics in total) and in the third stage, 300 people, including 150 men and 150 women, were randomly selected from the people treated with methadone in these selected centers. .... [27].
Used Devices & Materials
McGill pain scale [28, 29] with Cronbach's alpha 0.87, Connor and Davidson resilience scale [30] with Cronbach's alpha 0.84, failure tolerance questionnaire [31, 32] with Cronbach's alpha 0.72, and Bass and Perry aggression questionnaire [33, 34] with Cronbach's alpha of 0.71, were the tools used in this study.
Statistical Analysis
After examining the assumptions of parametric tests such as continuity of variables in terms of measurement and normalization of data distribution using Kolmogorov-Smirnov test and establishing homogeneity of variance of variables also the similarity of the two groups in demographic variables of age, education, and work experience, Paired sample t-test was used for data analysis.
Finding by Text
The highest frequency among the 300 samples, (42%) was related to people between 22 and 26 years (126 people), with bachelor's degree (141 people; 47%) and 11 to 15 years of work experience (150 people; 50%) and the lowest frequency was between 32 and 36 years old, with Ph.D. and above 15 years of work experience (Table 1). The normality of the data distribution of variables was checked and confirmed by the Kolmogorov-Smirnov test (p>0.05). The mean of all variables of the study was different in men and women, but only the difference between pain perception, failure tolerance, and aggression with values was respectively 4.152±0.521, 4.208±0.303 and 3.621 21±0.211 which were significant in women and 3.258±0.359, 3.247±0.137, and 4.188±652 in men who treated with methadone maintenance program at the level of p<0.05 (Table 2). Mean values showed that in women, pain perception and tolerance of failure were more and less aggression compared to men (p<0.05) but no significant difference was observed between resilience between women and men (p >0.05; Table 2).
Main Comparison to the Similar Studies
According to the results of this study, for women, the process of quitting methadone is more difficult than for men. In general, the results of the study are consistent with studies that have confirmed gender differences in substance abuse disorders and their treatment [4] … [5]. Researchers have shown that the brain is a biological process that triggers addiction and the capacity to change behavior [35]. Therefore the perspective of the nervous system and biology improves the study from a scientific perspective. In explaining the results of the present study, this view has been tried to be considered. The first finding of the present study was a higher perception of pain in women addicted to methadone than men. Studies show that pain tolerance is lower in people with methadone addiction than in normal people [36]. While pain tolerance is different in men and women; although the difference in pain sensitivity and perception between men and women is partly due to social conditions and psychosocial factors, many laboratory studies have attributed this difference to biological mechanisms and sex hormones [37]. The results of studies show that gender differences in pain and its relief are due to an interaction between genetic, anatomical, physiological, neurological, hormonal, psychological, and social factors that regulate pain differently in both sexes [38]. ... [39, 40]. The present study also showed a higher rate of pain perception in women treated with methadone compared to men. This finding can be explained by examining the status of the menstrual cycle of women in the sample group and the effects of estrogen on pain sensation and perception and its interaction with the analgesic properties of methadone in women's pain tolerance. Another result showed that the resilience of addicted men and women treated with methadone was not different. Evidence shows that resilience is affected by gender and in comparison with men, women show different reactions in stressful situations [41]. However, such a result was not obtained in this study. Perhaps this difference can be related to the cultural, educational, and socio-economic status of the sample group. This result can also be attributed to the equal desire of men and women for withdrawal. This finding can be interpreted positively, as this lack of differences in the resilience of men and women in the process of quitting substance abuse can indicate a reduction in non-biological gender differences. Differences such as differences in psychological abilities as internal factors and differences in negative outlook and other cultural and social gender factors as external factors. Another finding of the present study was that failure tolerance was lower in women with methadone treatment substance abuse disorders compared to men. According to the behavioral inhibitor and behavioral activator brain systems presented in reinforcement sensitivity theory, the behavioral inhibitor system is more active in women than men. As a result, women are more likely to fail or feel frustrated. When addicted people are in the process of withdrawal, the activity of the behavioral inhibition system increases due to the lack of drugs, in other words, the lack of rewards. Increased activity of this system in men is considered inactivity in the male brain system and reduces the severity of the behavioral activation system, but in women, it doubles the activity of the inhibitory system and causes more severe failure symptoms in women. ... [42]. When quitting methadone, due to the presence of a pleasant stimulus with reward symptoms, namely methadone, the behavioral activation system in people quitting with methadone is activated. On the other hand, due to the limited consumption in terms of the amount of substance consumed and the time of consumption, the behavioral inhibition system becomes more active. The behavioral activation system has a facilitating role in the activity of the behavioral inhibition system and raises the level of activity of the behavioral inhibition system. Due to the higher level of behavioral inhibition system in women in normal situation, the increased activity of this system is doubled and leads to much greater failure in women treated with methadone than in men. The more severe the failure, the more difficult it is to tolerate and the more intolerant the failure, and this is what happens to women on methadone treatment compared to men. The latest finding of the present study was a higher rate of aggression in methadone-addicted men compared to their female counterparts. Higher levels of anger, aggression, and aggressive and harmful behaviors in men than in women can be attributed to higher levels of the male hormone testosterone in men. In addition, men are considered to be stronger and more superior due to their mainly larger physical appearance, more voluminous muscles, and more physical strength. ... [43]. Because in the present study, men felt more failure than women, consequently, the aggression that led to the feeling of failure was more in men than women.
Limitations
The limitations of the present study include not considering variables such as marital status, type of job and income, having or not having children, duration of addiction, amount of substance used before entering the treatment plan, number of withdrawal measures, and types of previous methods for quitting, that can have many effects on the study.
Suggestions
It is suggested that in future research, anxiety and anger control training be performed in treated men. The implementation of failure protocols based on different psychological approaches in women treated with methadone is also suggested in future studies.
Conclusions
In the process of methadone withdrawal, women perceive more pain and tolerate less failure than men, and men are more aggressive than women. Therefore, the process of methadone withdrawal seems to be more difficult for women than men.
Clinical & Practical Tips in Police Medicine
The use of the results of the present study in the treatment of criminals with drug abuse can be expressed according to their gender in police medical centers and other medical units of the police force.
Acknowledgments
We would like to thank all the participants who contributed to this research.
Conflict of Interest
The authors state that there is no conflict of interest in the present study.
Funding Sources
The present study had no financial support.
Table 1) Demographic characteristics of the two groups
| Variable | Level | Total frequency | Total percentage | The frequency of women | frequency of men |
| Age | 18 to 21 years | 54 | 18 | 26 | 28 |
| 22 to 26 years | 126 | 42 | 64 | 62 | |
| 27 to 31 years | 108 | 36 | 55 | 53 | |
| 32 to 36 years | 12 | 4 | 5 | 7 | |
| Education | High school Diploma and diploma | 54 | 18 | 24 | 30 |
| Bachelor | 141 | 47 | 76 | 65 | |
| MA | 69 | 23 | 37 | 32 | |
| PHD | 36 | 12 | 13 | 23 | |
| Work Experience | 0 to 10 years | 120 | 40 | 63 | 57 |
| 11 to 15 years | 150 | 50 | 73 | 77 | |
| 15 years and up | 30 | 10 | 14 | 16 |
Table 2) Descriptive indicators of research variables by group
with the results of independent t-test
| Variable | Women | Men | Comparison of means of the two groups | |||
| Mean | The standard deviation | Mean |
The standard deviation | t (58) | p | |
| Perception of pain | 4.152 | 0.521 | 3.258 | 0.359 | 2.805 | 0.007 |
| Resilience | 3.961 | 0.357 | 3.651 | 0.198 | 1.514 | 0.136 |
| Tolerance of failure | 4.208 | 0.303 | 3.247 | 0.137 | 5.398 | 0.0005 |
| Violence | 3.621 | 0.211 | 4.188 | 0.652 | 4.122 | 0.0005 |
Article number: e12
Article Type: Original Research |
Subject:
Addiction & Substance Abuse
Received: 2021/10/29 | Accepted: 2022/02/11 | Published: 2022/03/7
Received: 2021/10/29 | Accepted: 2022/02/11 | Published: 2022/03/7
Extended Abstract [HTM 59 KB] (39 Download)
References
1. Che X, Cai J, Liu Y, Xu T, Yang J, Wu C et al. Oxytocin signaling in the treatment of drug addiction: Therapeutic opportunities and challenges. Pharmacol Ther. 2021;223:107820. doi. 10.1016/j.pharmthera.2021.107820. [DOI:10.1016/j.pharmthera.2021.107820] [PMID]
2. Almutairi AMM. Principles of drug addiction treatment. Int J Med Dev Ctries. 2021;5(2):1523-7. doi.org/10.24911/IJMDC.51-1609883100. [DOI:10.24911/IJMDC.51-1609883100]
3. Cao P, Zhang Z, Zhong J, Xu S, Huang Q, Fan N. Effects of treatment status and life quality on anxiety in MMT patients. Subst Abuse Treat Prev Policy. 2021;16:1-8. doi.org/10.1186/s13011-021-00343-4. [DOI:10.1186/s13011-021-00343-4] [PMID] [PMCID]
4. Pourmohseni Koluri F, Haghshenas A, Asadi S. A comparison of brain-behavioral systems and gender differences among addicted and non-addicted persons. Adv Cogn Sci. 2011;13(2):9-22. Persian. http://icssjournal.ir/article-1-344-fa.html.
5. LaGrotta C. Gender differences in addiction. Curr Addict Rep. 2021;8:64-70. doi.10.1007/s40429-021-00355-x. [DOI:10.1007/s40429-021-00355-x]
6. Agterberg S, Schubert N, Overington L, Corace K. Treatment barriers among individuals with co-occurring substance use and mental health problems: Examining gender differences. J Subst Abuse Treat. 2020; 112:29-35. doi. 10.1016/j.jsat.2020.01.005. [DOI:10.1016/j.jsat.2020.01.005] [PMID]
7. Gray JA, McNaughton N. The neuropsychology of anxiety: An enquiry in to the functions of the Septo-Hippocampal System. 2th ed. Oxford: Oxford University Press. 2003; 448p. https://global.oup.com/academic/product/the-neuropsychology-of-anxiety 9780198522713? cc=us&lang=en&. [DOI:10.1093/acprof:oso/9780198522713.001.0001]
8. Franken IHA, Muris P. BIS/BAS personality characteristics and college students' substance use. Pers Individ Differ. 2006;40(7):1497-503. doi.org/10.1016/j.paid.2005.12.005. [DOI:10.1016/j.paid.2005.12.005]
9. Bijtebier P, Beck I, Clase L, Vandereycken W. Grays' reinforcement sensitivity theory as a framework for research on personality-psychopathology association. Clin Psychol Rev. 2009;29(5):421-30. doi. 10.1016/j.cpr.2009.04.002. [DOI:10.1016/j.cpr.2009.04.002] [PMID]
10. Cahill CM, Lueptow L, Kim H, Shusharla R, Bishop A, Evans CJ et al. Kappa opioid signaling at the crossroads of chronic pain and opioid addiction. Handbook Exp Pharmacol. 2022;271:315-50. doi. 10.1007/164_2021_434. [DOI:10.1007/164_2021_434] [PMID]
11. Massaly N, Markovic T, Creed M, Al-Hasani R, Cahill CM, Moron JA. Pain, negative affective states and opioid-based analgesics: Safer pain therapies to dampen addiction. Inter Rev Neurobiol. 2021;157:31-68. doi. 10.1016/bs.irn.2020.09.002. [DOI:10.1016/bs.irn.2020.09.002] [PMID]
12. Khammarnia M, Peyvand M. The reasons of return to drug addiction and suggested solutions among the people referring to rehabilitation centers: A qualitative study. J Rafsanjan Univ Med Sci. 2018;17(6):523-38. Persian. http://journal.rums.ac.ir/article-1-4050-en.html
13. Akbaribooreng M, Dalakeh M, Saberi R, yasbelaghi B. The effectiveness of curriculums based on cognitive-behavioral therapy in the increase of self-efficacy and resilience among the addicts under methadone maintenance treatment. Res Addic. 2016;10(38):103-17. [Persian]. http://etiadpajohi.ir/article-1-639-fa.html.
14. Conner KM, Davidson JRT. Development of a new resilience scale: The Conner-Davidson Resilience Scale (CD - RISC). Depress Anxiety. 2003;18:76-82. [DOI:10.1002/da.10113] [PMID]
15. Croff JM, Beaman J. Family resilience and recovery from opioids and other addictions. Berlin: Springer. 2021. https://link.springer.com/book/10.1007/978-3-030-56958-7 [DOI:10.1007/978-3-030-56958-7]
16. Sadeghi S, Fathi A. Developing a structural model of the role of social health on high-risk behaviors of young people mediated by resilience: social order. J Police Med. 2021;10(4):255-62. http://dx.doi.org/10.30505/10.4.255
17. Roozgard, F, Sadeghi, E. investigating the relationship between failure tolerance and resilience of parents of exceptional children. Third National Conference on Psychology, Education and Lifestyle. Qazvin, Iran. 2019. https://civilica.com/doc/1020834
18. Vasquez TES, McAuley RJ, Gupta NS, Koshy S, Marmol-Contreras Y, Green TA. Lever-press duration as a measure of frustration in sucrose and drug reinforcement. Psychopharmacol. 2021;238(4);959-68. doi.10.1007/s00213-020-05742-2. [DOI:10.1007/s00213-020-05742-2] [PMID] [PMCID]
19. Hooshmandi F, Naemi A. The effectiveness of self-forgiveness training with a religious approach on vitality and failure tolerance of mothers of children with intellectual and developmental disabilities. J Modern Psychol Res. 2019;13(52):305-26. Persian. https://psychologyj.tabrizu.ac.ir/article_8636.html?lang=en
20. Rahimi N, Afsharinia K. Prediction of psychological resilience based on degree of differentiation and frustration tolerance in the elderly. Aging Psychol. 2017;3(2):127-36. [Persian]. https://jap.razi.ac.ir/article_761.html?lang=en
21. Yu S, Mao S, Wu AMS. The interplay among stress, frustration tolerance, mindfulness, and social support in Internet gaming disorder symptoms among Chinese working adults. Asia Pac Psychiatr. 2018;10(4):e12319. doi.10.1111/appy.12319. [DOI:10.1111/appy.12319] [PMID]
22. Ramirez-Castillo D, Garcia-Roda C, Guell F, Fernandez-Montalvo J, Bernacer J, Morón I. Frustration tolerance and personality traits in patients with substance use disorders. Front Psychiatr. 2019;1-12. [DOI:10.3389/fpsyt.2019.00421] [PMID] [PMCID]
23. Berkowitz L. A cognitive-neoassociation theory of aggression. The handbook of theories of social psychology. Sage Publications Ltd. 2012;99-117p. https://psycnet.apa.org/doi/10.4135/9781446249222.n31 [DOI:10.4135/9781446249222.n31]
24. Amiri M, Sadeghi Z, Sadeghi E, Khosravi A. Relationship between assertion and aggression with addiction potential: a cross-sectional study in 2019. Osong Public Health Res Perspect. 2020;11(4):231. doi. 10.24171/j.phrp.2020.11.4.12. [DOI:10.24171/j.phrp.2020.11.4.12] [PMID] [PMCID]
25. Akçay BD, Akçay D. What are the factors that contribute to aggression in patients with co-occurring antisocial personality disorder and substance abuse? Arch Clin Psychiatr. 2020;47(4):95-100. doi. 10.1590/0101-60830000000240. [DOI:10.1590/0101-60830000000240]
26. Safari F. Addiction and women gender differences concerning drug abuse and its treatment. Res addict. 2003;1(2):119-39. [Persian]. http://etiadpajohi.ir/article-1-492-fa.html.
27. Wilson Van Voorhis CR, Morgan BL. Understanding power and rules of thumb for determining sample size. Tutor Quant Methods Psychol. 2007;3(2):43‐50. doi.10.20982/tqmp.03.2.p043. [DOI:10.20982/tqmp.03.2.p043]
28. Melzak R. (1975). The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1975;1(3):277-99. doi. 10.1016/0304-3959(75)90044-5. [DOI:10.1016/0304-3959(75)90044-5]
29. Kosravi M, Sadighi S, Moradi Alamdari Sh, Zendehdel K. Persian-McGill pain questionnaire translation, adaptation and reliability in cancer patients: a brief report. Tehran Univ Med. 2013;71(1):53-8. [Persian]. http://tumj.tums.ac.ir/article-1-38-fa.html.
30. Samani S. Study of Reliability and Validity of the Buss and Perry's Aggression Questionnaire. IJPCP. February 2008;13(4):359-365. Persian. http://ijpcp.iums.ac.ir/article-1-356-fa.html.
31. Harrington, N. The frustration discomfort scale: Development and psychometric properties. Clin Psychol Psychother. 2005; 12(5):374-387. doi.org/10.1002/cpp.465. [DOI:10.1002/cpp.465]
32. Babaraisi, MA. Validation of Failure Tolerance Questionnaire. Tehran: Azmoon Yarpouya. 2014. Persian. http://www.azmonyar.com/Pro002.aspx
33. Buss AH, Perry M. The aggression questionnaire. J Pers Soc Psychol. 1992;63:452-9. doi. 10.1037//0022-3514.63.3.452. [DOI:10.1037/0022-3514.63.3.452] [PMID]
34. Najarian B, Davoodi I. Construction and validation of SCL-25 (short-term form SCL-90-R). J Psychol. 2002;5(2):136-49. Persian. https://www.sid.ir/fa/journal/ViewPaper.aspx?id=27176
35. Heilig M, MacKillop J, Martinez D, Rehm J, Leggio L, Vanderschuren LJ. Addiction as a brain disease revised: why it still matters, and the need for consilience. Neuropsychopharmacolo. 2021;46:1715-23. https://www.nature.com/articles/s41386-020-00950-y [DOI:10.1038/s41386-020-00950-y] [PMID] [PMCID]
36. Compton P, Charuvastra VC, Kintaudi K, Ling W. Pain responses in methadon-maintained opioid abusers. J Pain Sym Manag. 2000;20(4):237-45. doi. 10.1016/s0885-3924(00)00191-3. [DOI:10.1016/S0885-3924(00)00191-3]
37. Wiesenfeld-Hallin, Z. Sex differences in pain perception. Gend Med. 2005;2(3):137-45. doi. 10.1016/s1550-8579(05)80042-7. [DOI:10.1016/S1550-8579(05)80042-7]
38. Pieretti S, Di Giannuario A, Di Giovannandera, R, Marzoli F, Piccaro G, Minosi P, Aloisi AM. Gender differences in pain and its relief. Ann Ist Super Sanita. 2016;52(2):184-9. doi. 10.4415/ANN_16_02_09.
39. Lee CW, Ho IK. Sex differences in opioid analgesia and addiction: interactions among opioid receptors and estrogen receptors. Mol Pain. 2013;8(9):45. doi.10.1186/1744-8069-9-45. [DOI:10.1186/1744-8069-9-45] [PMID] [PMCID]
40. Chiang YC, Wang RY, Huang CL, Chen SH, Ho WJ et al. Reduced dosing and liability in methadone maintenance treatment by targeting estrogen signal for morphine addiction. J Cell Mol Med. 2017;21(12):3552-64. doi. 10.1111/jcmm.13266. [DOI:10.1111/jcmm.13266] [PMID] [PMCID]
41. Jebraeili H, Habibi M, Nazemi A. Mediating role of resilience and tendency to addiction regarding the effect of gender on substance use. J Res Health. 2019;9(3):236-45. [Persian]. http://dx.doi.org/10.29252/jrh.9.3.236 [DOI:10.29252/jrh.9.3.236]
42. Corr PJ. Testing problems in JA, Gray's personality theory: A commentary on Matthews and Gilliland (1999). Person Individ Differ. 2001;30(2): 333-52. doi.org/10.1016/S0191-8869(00)00028-3. [DOI:10.1016/S0191-8869(00)00028-3]
43. Muñoz-Reyes JA, Polo P, Valenzuela N, Pavez P, Ramirez-Herrera O, Figueroa O, Rodrigez-Sickert c, Diaz D, Pita M. The Male Warrior Hypothesis: Testosterone-related Cooperation and Aggression in the Context of Intergroup Conflict. Sci Rep. 2020; 10:375. doi.org/10.1038/s41598-019-57259-0 [DOI:10.1038/s41598-019-57259-0] [PMID] [PMCID]
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