Background: Peripartum Cardiomyopathy (PPCM) is a life-threatening heart disease which appears with heart failure and function reduction of left ventricular in late pregnancy or in the first five months postpartum in women with no history of heart disease. Case Report: The report is about the fourth pregnancy of a 31-year-old woman who has had 3 healthy children and has not been observed by any Gynecologists and Obstetrics or health center during pregnancy and admitted to hospital for delivery. According to her medical history, the mother had no disease and had Normal Vaginal Delivery (NVD) in previous pregnancies. The patient with placental abruption, Fetal distress and failure of progression diagnosis was transferred to the Operating Room (OR) for Caesarean Section (CS). After Caesarean Section, she was involved in dyspnea and acute pulmonary edema during recovery. Having been diagnosed with postpartum cardiomyopathy by cardiologist, the patient was transferred to ICU and died less than 24 hours. Results: Physicians, evaluate to the cardiologist. Conclusion: Physicians, midwives, nurses, and also patients should be aware that a pregnant mother could be at the risk of a severe cardiomyopathy with acute onset heart failure, despite her clear medical history of heart problems. In Prenatal care, therefore, it is necessary for physicians and midwives to pay attention to the symptoms of dyspnea on exertion and functional class of pregnant mothers and in case of reduced performance, the mother must be referred to the cardiologist.